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BIOTRAK Real-Time

Viable Particle Counter

Application Notes


TSI has a variety of application notes available to help you learn more about the BioTrak® Real-Time Viable Particle Counter and its applications. Topics include:

  • Principle of Operation
    The BioTrak Real-Time Viable Particle Counter is a full featured instrument that detects the total number of particles in the air as well as determining which of those particles are viable in nature. It incorporates a particle collection filter so the optically analyzed particles are available for subsequent speciation analysis. The BioTrak Real-Time Viable Particle Counter is built upon proven technologies leveraging TSI’s experience in particle measurement theory, instrument development, and calibration.
 
  • Importance of a Good Non-Viable Measurement
    A non-viable airborne particle counter is a misnomer. Current airborne particle counting technology such as found in the TSI AeroTrak® particle counters, size and count all particles that pass through its viewing volume, it does not matter whether the particle is viable or non-viable. When an airborne particle counter displays 1 particle count at 5 µm it may or may not be viable, the instrument is unable to tell the difference. Now, the BioTrak  Real-Time Viable Particle Counter can tell you the difference.
 
  • Discrimination Capability
    The BioTrak Real-Time Viable Particle Counter is a full featured instrument that detects the total number of particles in the air as well as determining which of those particles are viable in nature. It incorporates three discrimination parameters into its viability detection algorithms that greatly enhance its ability to correctly classify viable versus non-viable particles in real-time.
 
  • Sample and Collection Efficiency
    This application note presents issues related to aerosol sample and collection efficiency during various stages of the aerosol path in the BioTrak Real-Time Viable Particle Counter, and relates those efficiencies to other methods, like Active Air Samplers. When applying a viable particle counter, or any particle device in a cleanroom, proper characterization of the product is important so results can be understood, leading to root cause identification, and ultimately to continual improvement.
 
  • Facility Monitoring Systems
    This application note will demonstrate how real-time viable particle count data will lead to improved root cause investigations when a BioTrak Real-Time Viable Particle Counter is integrated into an FMS system. Improved root cause investigations and the resulting increased process knowledge is in line with current regulatory initiatives and expectations.
 
  • Purpose & Application of ISO 21501-4 
  • This application note highlights ISO 21501-4 as it provides a calibration procedure and verification method for particle counters, so as to minimize in the inaccuracy in the measurement result by a counter, as well as the differences in the results measured by different instruments. The implementation of this standard forced improvements in calibration systems and, often, improvements in airborne particle counter design and performance. 
 
  • Root Cause Investigation Guidance
    This application note provides recommendations for how the BioTrak Real-Time Viable Particle Counter can be used to greatly improve the user's ability to identify a definitive root cause in the event of an airborne viable excursion---a common pitfall using traditional techniques. 
 
  • Evaluation Guidance
    This application note provides methodology for familiarizing the user with the operation of the BioTrak Real-Time Viable Particle Counter and for evaluating the data obtained against those produced by traditional methods. 
 

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